Publications

General Light-Induced Pd-Catalyzed Allylic C–H Alkylation of Internal Alkenes: Direct Access to Tertiary and Quaternary Carbon Centers

Subham Pradhan^#, Gaurav Prakash^#, Vladimir Gevorgyan*

J. Am. Chem. Soc. 2025, ASAP
Transition-Metal-Free Site-Selective β– and γ-C–H Borylation of Aliphatic Amines

Sumon Sarkar,# Nitish Kumar Deo,# Tong Zhang, and Vladimir Gevorgyan*

J. Am. Chem. Soc. 2025, 147, 40064–40070
Nickel-Catalyzed Cross-Dehydrogenative Coupling of Aldehydes and Alkenes toward Skipped Enones

Sidhant Wagulde^#, Pramod Rai^#, Vladimir Gevorgyan*

J. Am. Chem. Soc. 2025, 147, 34211–34217
Directed Halogen Atom Transfer (DIXAT): A Powerful Tool for Chemoselective Generation of Aryl Radicals toward Remote C(sp3)–H Functionalization of Aliphatic Amines.

Sidhant Wagulde, Kevin P. Quirion, Turki M. Alturaifi, Peng Liu*, Vladimir Gevorgyan*

J. Am. Chem. Soc. 2025, 147, 29367–29376
Nickel-Catalyzed Branched Hydroalkylation of Alkenes with Diazo Compounds

Nikita Kvasovs^#, Valeria Iziumchenko^#, Alistair J. Sterling, Vladimir Gevorgyan*

J. Am. Chem. Soc. 2025, 147, 8093–8100
Enantioselective Total Syntheses of Vallesamidine and Schizozygane Alkaloids

Gujjula V. Ramakrishna, Zurwa Latif, Filippo Romiti*

J. Am. Chem. Soc. 2025, 147, 4613−4623
Stereodivergent Synthesis of Pyridyl Cyclopropanes via Enzymatic Activation of Pyridotriazoles

Roy Satyajit, Yining Wang, Xinyi Zhao, Thakshila Dayananda, Jian-Min Chu, Yong Zhang*, Rudi Fasan*

J Am Chem Soc. 2024, 146, 19673-19679

Representative Work

Beyond Strain Release: Delocalization-Enabled Organic Reactivity

Alistair J. Sterling,* Russell C. Smith, Edward A. Anderson,* Fernanda Duarte*

J. Org. Chem. 2024, 89, 9979−9989
Stereoselective Construction of β-, γ- and δ-Lactam Rings Via Enzymatic C–H Amidation

Satyajit Roy, David A. Vargas, Pengchen Ma, Arkajyoti Sengupta, Ledong Zhu, Kendall N. Houk*, Rudi Fasan*

Nat. Catal. 2024, 7, 65-76
Biocatalytic Strategy for the Construction of sp³-Rich Polycyclic Compounds from Directed Evolution and Computational Modelling

David A. Vargas, Xinkun Ren, Arkajyoti Sengupta, Ledong Zhu, Satyajit Roy, Marc Garcia-Borràs, Kendall N. Houk*, Rudi Fasan*

Nat. Chem. 2024, 16, 817-826
Mechanistic Insights into the Origins of Selectivity in a Cu-Catalyzed C–H Amidation Reaction

Alistair J. Sterling*, Nicodemo R. Ciccia, Yifan Guo, John F. Hartwig*, Martin Head-Gordon*

J. Am. Chem. Soc. 2024, 146, 6168-6177
Catalytic Prenyl Conjugate Additions for Synthesis of Enantiomerically Enriched PPAPs

Shawn Ng, Casey P. Howshall, Thanh-Nhat Ho, Khanh Bin Mai, Yuebiao Zhou, Can Qin, Kai Ze Tee, Peng Liu*, Filippo Romiti*, Amir H. Hoveyda*

Science 2024, 386, 167-175
One-Pot Formal Carboradiofluorination of Alkenes: A Toolkit for
Positron Emission Tomography Imaging Probe Development

Mónica Rivas,# Sashi Debnath,# Sachin Giri, Yusuf M. Noffel, Xiankai Sun,* Vladimir Gevorgyan*

J. Am. Chem. Soc. 2023, 145, 19265−19273
Streamlined Strategy for Scalable and Enantioselective Total
Syntheses of the Eburnane Alkaloids

Gujjula V. Ramakrishna,† Larisa P. Pop,† Zurwa Latif, Harish K. V. Suryadevara, Luca Santo, Filippo Romiti*

J. Am. Chem. Soc. 2023, 145, 20062−20072
Asymmetric Intermolecular Allylic C–H Amination of Alkenes With Aliphatic Amines

Kelvin Pak Shing Cheung, Jian Fang, Kallol Mukherjee, Andranik Mihranyan, Vladimir Gevorgyan*

Science 2022, 378, 1207-1213