Our mission is to provide researchers with interests in organic synthesis, biocatalysis, and chemical biology with powerful tools for rapid reaction discovery optimization and for the chemical synthesis of diverse collections of bioactive compounds. This includes the application of high-throughput experimentation and machine-learning methods for the discovery of new catalytic systems for organic synthesis as well as chemoenzymatic synthesis, and their expeditious optimization to maximize yields, selectivity, and atom/step economy. The Center also aims to develop and deploy powerful platforms for accessing and exploring new chemical space through the synthesis of diverse collections of small molecules, including functionalized heterocycles, natural product derivatives and complex natural product like compounds.
Supported by the Cancer Prevention and Research Institute of Texas (CPRIT) and the University of Texas at Dallas, and nestled within the vibrant academic landscape of our institution, the HT-RDS Center constitutes a state-of-the-art facility meant to provide chemical innovation solutions to researchers and collaborators within the UTD community and other academic institutions